This is the SACE Honour Roll, listing every award, merit or prize won by South Australian SACE students in 2022, along with their school and subject details.
The report also includes significant Australian national awards and prizes such as the Australian Student Prize.
| 994 | Sabine, Alice | SA | Merit | Research Project B | |
| 995 | Sacca, Lucas Michael | SA | Merit | Modern History | |
| 996 | Saddi, Chandan | SA | Merit | Business Innovation | |
| 997 | Safi, Ibrahim | SA | Merit | Industry and Entrepreneurial Solutions | |
| 998 | Sagirov, Victoria Elly | SA | Merit | Integrated Learning A | |
| 999 | Sagirov, Victoria Elly | SA | Merit | Research Project B | |
| 1000 | Samchea, Talia Morokott | SA | Merit | Research Project B | |
| 1001 | Sampson, William Kane | SA | Merit | General Mathematics | |
| 1002 | Sampson, William Kane | Wudinna Area School | Wudinna | Gov of SA SACE Award | General Mathematics |
| 1003 | Sanderson-Bromley, Temaana Yunda | SA | Merit | Aboriginal Studies | |
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| 1004 | Sandery, Charlie Rose Mulholland | SA | Merit | Research Project B | |
| 1005 | Santoro, Kate | SA | Merit | General Mathematics | |
| 1006 | Santos, Josiah | SA | Merit | Research Project B | |
| 1007 | Santos, Stella | SA | Merit | Food and Hospitality | |
| 1008 | Sarre, Charlotte Anna | SA | Merit | Drama | |
| 1009 | Sarris, Samuel | SA | Merit | Philosophy | |
| 1010 | Sartor, Amelia | SA | Merit | Research Project B | |
| 1011 | Sartor, Daniella | SA | Merit | Research Project B | |
| 1012 | Sathish, Garima | SA | Merit | Research Project B | |
| 1013 | Saulwick, Alexandra Claire | SA | Merit | Earth and Environmental Science | |
| 1014 | Saunders, Maddison | SA | Merit | Research Project B | |
| 1015 | Saunderson, Rachel | SA | Merit | Integrated Learning B | |
| 1016 | Scamoni, Olivia Daniela | SA | Merit | Physical Education | |
| 1017 | Scardigno, Jayde | SA | Merit | Research Project B | |
| 1018 | Schaefer, Caitlin Paige | SA | Merit | Research Project B | |
| 1019 | Schapel, Flynn Sterling | SA | Merit | Research Project B | |
| 1020 | Scheide, Amara Jade | SA | Merit | Scientific Studies | |
| 1021 | Schiller, Claire Louise | SA | Merit | Research Project B | |
| 1022 | Schiller, Oskar Frederick | SA | Merit | Research Project B | |
| 1023 | Schimizzi, Francesco | SA | Merit | English | |
| 1024 | Schultz, Jessica Lily Wright | SA | Merit | Physical Education | |
| 1025 | Schwarz, Meg Alexandra | SA | Merit | Research Project B | |
| 1026 | Scinto, Daniel Connor | SA | Merit | Business Innovation | |
| 1027 | Scinto, Daniel Connor | SA | Merit | English | |
| 1028 | Scinto, Daniel Connor | SA | Merit | Physical Education | |
| 1029 | Scott, Keira Storm | SA | Merit | Research Project B | |
| 1030 | Scott-Young, Hamish Angus | SA | Merit | Workplace Practices | |
| 1031 | Searle, Kiara | SA | Merit | Physical Education | |
| 1032 | Segal, Zara | SA | Merit | Research Project B | |
| 1033 | Selkrig, Hailey | SA | Merit | English | |
| 1034 | Senarath Parana Yapa, Kavindya Nethmini | SA | Merit | Integrated Learning B | |
| 1035 | Senarath Parana Yapa, Kavindya Nethmini | SA | Merit | Workplace Practices | |
| 1036 | Seneca, Mark | SA | Merit | Modern History | |
| 1037 | Seppelt, Alice Rose | SA | Merit | General Mathematics | |
| 1038 | Sethi, Karan | SA | Merit | Chemistry | |
| 1039 | Sethi, Karan | SA | Merit | Physics | |
| 1040 | Sewart, Nathan | SA | Merit | Research Project B | |
| 1041 | Shah, Het | SA | Merit | Biology | |
| 1042 | Shah, Het | SA | Merit | Chemistry | |
| 1043 | Shah, Janviben (Janvi) | SA | Merit | Research Project B | |